Real-world effectiveness of abobotulinumtoxinA (Dysport®) in adults with upper limb spasticity in routine clinical practice: an observational study

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Effects of repeated abobotulinumtoxinA injections in upper limb spasticity

INTRODUCTION The efficacy of single injections of abobotulinumtoxinA (Dysport) is established in adults with upper limb spasticity. In this study we assessed the effects of repeated injections of abobotulinumtoxinA over 1 year. METHODS Patients (n = 258, safety population) received 500 U, 1,000 U, or 1,500 U (1,500-U dose included 500-U shoulder injections) for up to 4 or 5 treatment cycles. ...

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Systematic Literature Review of AbobotulinumtoxinA in Clinical Trials for Adult Upper Limb Spasticity

OBJECTIVE The aim of this study was to elucidate clinical trial efficacy, safety, and dosing practices of abobotulinumtoxinA (ABO) treatment in adult patients with upper limb spasticity (ULS). METHODS A systematic literature review was performed to identify randomized controlled trials and other comparative clinical studies of ABO in the treatment of adult ULS published in English between Jan...

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Clinical Management of Upper Limb Spasticity

Case Report A 67-year-old right-handed male who had suffered an ischemic left basal ganglia stroke with right hemiparesis was evaluated for post-stroke rehabilitation therapies. He had undergone comprehensive inpatient rehabilitation six months earlier. When he was discharged home, he required supervision for upper and lower body dressing but was at a “modified independent” level for ambulation...

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Systematic Literature Review of AbobotulinumtoxinA in Clinical Trials for Lower Limb Spasticity

To elucidate clinical trial efficacy, safety, and dosing practices of AbobotulinumtoxinA (ABO) treatment in adult patients with lower limb spasticity.A systematic literature review was performed to identify randomized controlled trials of ABO in the treatment of adult lower limb spasticity.Of the 295 records identified, 6 primary publications evaluated ABO for the management of lower limb spast...

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In this post-hoc analysis of the ULIS-II study, we investigated factors influencing person-centred goal setting and achievement following botulinum toxin-A (BoNT-A) treatment in 456 adults with post-stroke upper limb spasticity (ULS). Patients with primary goals categorised as passive function had greater motor impairment (p < 0.001), contractures (soft tissue shortening [STS]) (p = 0.006) and ...

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ژورنال

عنوان ژورنال: Neurologia i Neurochirurgia Polska

سال: 2020

ISSN: 1897-4260,0028-3843

DOI: 10.5603/pjnns.a2020.0004